From the Ulm direction:

B 311 federal highway in the direction of Tuttlingen/Freiburg to Mengen.

From the Stuttgart direction:

B 27 federal highway to Reutlingen, followed by B 32 via Sigmaringen to Mengen.

From the Munich direction:

A 96 federal motorway to Memmingen, followed by A 7 to the Berkheim exit, B 312 to Biberach, then via Bad Saulgau to Mengen.